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Interesting Facts about
Oral Supplement Absorption 

Absorption Rate Basics

  • When you swallow a pill, not all of it is absorbed. Some is destroyed by stomach acid, some passes through unabsorbed, and some is metabolized (broken down) before it ever reaches your bloodstream.

  • The percentage that actually enters circulation is called "BIOAVAILABILITY".

Typical Ranges for Oral Supplements (Pills/capsules)

Supplement Type

Estimated % Absorption (Bioavailability)

% THAT NEVER MAKES IT INTO YOUR SYSTEM

VITAMINS          
(water-soluble
e.g. C, B-complex)                     50 - 90%                         10 - 50% LOST

Fat-Soluble Vitamins               10 - 60%                        40 - 90% LOST
(A, D, E, K)                                                                                   (depending on 
                                                                                                                   fat intake)          
MINERALS                                                                                    
(e.g. zinc, magnesium,            10 - 50%                         50 - 90% LOST
  iron)           
                 
HERBAL EXTRACTS /                      5 - 30%                         70 - 95% LOST
PLANT COMPOUNDS            (often very low)       
                     
AMINO ACIDS
(like L-glutamine)                      70 - 90%                          10 - 30% LOST

PROBIOTICS                                        <10%                                      >90% LOST
                                                               (less than survives stomach acid)
VITAMINS
-> Estimated  Absorption 50-90%
-> % that never makes it to your system:  10-50% LOST
Water-soluble (e.g. vitamins C, B-complex)
-> Estimated  Absorption <10% (Less than 10% survives stomach acid)
-> % that never makes it to your system:   >90% LOST
Fat-soluble (e.g. vitamins A, D, E, K)
-> Estimated  Absorption 10-60%
-> % that never makes it to your system:  40-90% LOST (depending on fat intake) 
MINERALS
(e.g. zinc, magnesium, iron)
-> Estimated  Absorption 10-50%
-> % that never makes it to your system:  50-90% LOST
HERBAL EXTRACTS
/ PLANT COMPOUNDS
-> Estimated  Absorption 5-30%
-> % that never makes it to your system:  70-95% LOST
AMINO ACIDS
(like L-glutamine)
-> Estimated  Absorption 70-90%
-> % that never makes it to your system:  10-30% LOST
PROBIOTICS
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